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ADAM METALLOPEPTIDASES WITH THROMBOSPONDIN TYPE 1 MOTIF PROTEINS
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DeCS
Descriptor
English
:
ADAMTS Proteins
Descriptor
Spanish
:
Proteínas ADAMTS
Descriptor
Portuguese
:
Proteínas ADAMTS
Synonyms
English
:
A Disintegrin And Metalloproteinase With Thrombospondin Motifs Proteins
ADAMTS Proteases
ADAMTS-Like Proteins
ADAMTSL Proteins
Adam Metallopeptidases With Thrombospondin Type 1 Motif Proteins
ADAMTS Like Proteins
Tree Number:
D08.811.277.656.675.374.102.500
D09.400.430.500.500
D12.776.395.033.500
D12.776.860.300.085
Definition
English
:
A subfamily of ADAM proteases that are distinguished by the presence of one or more
THROMBOSPONDIN
type-1 repeats (TSRs). These are three-strand motifs that contain characteristic
TRYPTOPHAN
,
ARGININE
, and
CYSTEINE
residues respectively. In contrast to
ADAM proteins
, which reside on CELL
MEMBRANES
, ADAMTS proteases are secreted and function in the
EXTRACELLULAR MATRIX.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56485
Unique Identifier:
D000071096
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS